The role of a negative energy balance in cows after calving in the pathogenesis of uterine inflammation

The article presents the results of a study influence negative energy balance in cows transition period development postpartum uterine pathologies. On sonogram, metritis is presented as hypoechoic uniform thickening layers wall. With pyometra, thinning wall occurs. sonograms obtained during study, cavities considerable diameter (average 67.8 ± 4.6 mm) with content, presence hyperechoic inhomogeneous inclusions varying echo intensity, are visualized. During histological examination biopsy, it was determined that proportion integumentary epithelium pyometra and higher than clinically healthy animals. Changes were also noted regarding glands assessing overall structure endo metrium. metritis, this indicator 5.22 0.03%, 4.07 0.01%, which more 7 times lower when same co ws without clinical signs . A change these indicators indicates degenerative - dystrophic processes uterus, including glands, occur combination catarrhal -purulent lesions uterus. As result blood tests, we found purulent-catarrhal inflammation uterus newborn occurs against background oxidative stress. It concentration catalase increased by 43.0% (p<0.05). Also, sick showed significant increase content malondialdehyde In contrast to data from patients catarrhal-purulent decrease vitamin C – 30.9% (p<0.05) E 2.02 (p<0.01) cows, number changes revealed biochemical serum, indicating violation various types metabolism, particular dysproteinemia, hypercholesterolemia an enzyme activity.